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Sanofi Group mRNA - Scientist, Preclinical Immunology - Vaccine in Waltham, Massachusetts

In the race for the future of health – The Sanofi mRNA Center of Excellence ( CoE )

At Sanofi, we chase the miracles of science, and we know mRNA has a role to play in the future of health. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines and treatments for more people faster than before.

That’s why we’re looking for bold, optimistic world-changers to join our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 450 dedicated employees, and focusing on implementing an integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams.

Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology!

Role and Responsibility

  • Design and execute preclinical research strategies to evaluate the vaccine candidate immunogenicity, reactogenicity, efficacy and mechanism of action using various primary cell cultures and animal studies including mice and NHPs

  • Critically analyze, interpret, and report experimental results; draw appropriate conclusions and design next steps

  • Present results and strategies within the department, externally, and to internal governance committees as required.

  • Provide expertise in immunology and mRNA technology to internal project teams and committees as scientific functional lead

  • Ensure that the group maintains current awareness in area of expertise, enhance the scientific credibility

  • Contribute to the writing of protocols, reports, and other documents when appropriate

  • Should be able to manage time effectively to perform multiple projects at one time

  • Desire to work in a fast-paced environment

  • Excellent organizational and communication skills and carry strong analytical and problem-solving skills

  • Supervise Associate Scientist(s) and/or Research Associate(s) as needed

Qualifications/ Education & work experience

  • Ph.D. or MSc in immunology or related field. 2-3 years of experience is desirable.

  • Independence in experimental design and execution, data analysis, interpretation, and presentation of in vitro/in vivo study analysis of immune responses

  • Proficiency with multiple cutting-edge technologies to assess immune cell function including, but not limited to, cell imaging, ELISA/ELISOPT, cytotoxicity assays, multi-parameter flow cytometry, Luminex technologies

  • Desirable skills include MSD, HAI, Microneutralization, automation of liquid handling systems

  • Proficiency in performing functional antibody assays for viral vaccine

  • Ability to be self-motivated and accomplish job tasks with little supervision

  • Demonstrate Play to Win Culture Behaviors

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.

According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.