Massachusetts Jobs

About the Department

The Global Nucleic Acid Therapies area strives to be a global leader in nucleic acid therapeutics by developing innovative technology platforms and molecules that translate into novel genetic medicines to improve patients' lives. 

Our mission is to bring curative and disease modifying therapies to individuals liv-ing with serious chronic conditions. We are a global team with locations in Massachusetts (Greater Boston Research & Early Development Hub), Colorado and Copenhagen, pushing technological innovation to expand the RNA and gene therapy application space. Our proprietary GalXC™ and GalXC-Plus™ RNAi technologies have the potential to address conditions that are difficult or impossible to treat with other modalities. The value chain spans from early research to phase 1 clinical studies.

Established as a Transformational Research Unit (TRU), Global Nucleic Acid Therapies is a unique organization within Novo Nordisk Research & Early Development that brings together the best of both worlds – the agility, collaborative pioneering spirit and calculated risk-taking profile of a biotech along with the scale, resources and capabilities of a global leader in drug development. We are a team of inventive and entrepreneurial thinkers pushing the boundaries of science. Together, we are driving change. Are you ready to make a difference?

The Position

Participating in shaping our overall research strategy and supporting numerous projects as a member of the Discovery Research team. Collaborating cross-functionally to promote efficient operations in a high-volume on-site laboratory and animal care facility.

Relationships

This position reports to the Senior Scientist.

Essential Functions

• siRNA drug candidate screening, hit identification, and lead optimization, Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays RNA extraction and RT-qPCR

• In vivo drug candidate testing (e.g. mouse dosing; sample analysis)

• Work closely with GNAT research team members to quickly and effectively address critical questions related to the efficacy of our drugs

  Physical Requirements

  0-10% overnight travel required.

  Qualifications

• Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR)

• Experience with RNAi is preferred; experience with in vitro screening is preferred

• Experience with in vivo methodologies is highly preferred (e.g., mouse handling, subcutaneous injection, intravenous injection, sample analysis, histology)

• Experience with RNAi and in vitro screening is preferred

• The individual should have strong oral and written communication skills and a demonstrated ability to contribute effectively to group projects in a team-oriented environment

• The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected

  We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

  At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

  Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

  If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.