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Takeda Pharmaceuticals Staff Engineer in Cambridge, Massachusetts

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Job Description

About the Role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Synthetic Molecule Process Development (SMPD) is responsible for the development of robust, sustainable and cost-effective processes for the manufacture of new synthetic molecule pharmaceuticals, along with methods for achieving and controlling high standards of purity and quality.

The successful candidate will be responsible for aspects of reaction & particle engineering including the development of scale down models for the study of unit operations as well as technical transfer to external contract manufacturing organizations. They will be responsible for using process analytical technologies (PAT) in combination with mathematical models (both statistical & first principle) to enhance process understanding to effectively develop/optimize/scale-up and troubleshoot processes. The Staff Engineer will develop scale-down equipment and help implement innovative advanced process control strategies for both batch and continuous processes.

They will be recognized as a technical resource within PCD and utilize his/ her technical expertise to contribute across pipeline projects. The Staff Engineer will also be responsible for helping advance the department’s key technologies and define him/ herself as a subject matter expert in specific areas. He/ she will be responsible for managing outsourced activities as well as representing Takeda in pre-competitive collaborations with academic and industrial partners.


  • Independently designs and executes complex experimental protocols and reports results.

  • Owns a technical skill in its entirety and contributes significantly and independently to project work which may include multiple projects within functional area.

  • Provides technical leadership to project teams within area of expertise and commits resources to execute specific project tasks.

  • Reviews, interprets and communicates data cross functionally within pharmaceutical sciences and project teams.

  • Assists with the development of project strategy and communicates complex data/decisions within department and cross functionally as necessary.

  • Identifies process trends, recommends and implements new technologies and innovations.

  • Recognized as a technical expert and resource within function.

  • Coordinates and leads technology transfer to internal or external manufacturing sites.

  • Responsible for authoring relevant sections of regulatory documents, validation plans, reports and peer reviewed manuscripts.

  • Proactively identifies vendors and builds relationships to gain access to technologies as needed to deliver on pipeline goals.

  • Manages key vendor relationships across multiple projects as appropriate, and proactively affects resolution of issues arising at vendors.

  • Represents Takeda and is an active member on pre-competitive collaborations with academic and industrial partners.

Education and Experience:


  • A Ph.D. degree with 0+ years of academic, post-doctoral or pharmaceutical industry experience; an MS degree with 3+ years of pharmaceutical industry experience; or a BS degree with 5+ of pharmaceutical industry experience. Degrees in chemical engineering required.

  • Experience in the use of mathematical, both statistical and first principle, models preferred

  • Experience in building reaction kinetic models as well as process models preferred

  • Experience in building laboratory and pilot plant equipment a plus

  • Experience in the use of process analytical technologies (FT-IR, NIR, FBRM, UV-vis, etc.) preferred

  • Experience in building chemometric models a plus

  • Experience working in a pilot plant a plus

  • Experience in working in a multi-disciplinary team environment

  • Proven scientific track record through presentations at scientific conferences and publication of pier reviewed manuscripts

Knowledge and Skills:

  • Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems using appropriate information and, determine causes and possible solutions

  • Teamwork -- Ability to work well on global cross-functional teams.

  • Communication Skills -Able to expresses one’s self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates with senior management; technical writing skills to support authorship and approval of internal technical documents

  • Organization – Exercises good time management and prioritization skills to balance multiple project and departmental objectives

  • Technical - Subject matter expertise in a specific scientific area or areas.

  • Knowledge Sharing - Ability to capture knowledge within the organization; improves solutions, processes, and deliverables through use of information; improves information capital by contributing experience, theories, deliverables, and models for others to use

  • Resource Management -Project management skills; ability to manage one’s time within individual, departmental

What Takeda can offer you:

  • Comprehensive Healthcare: Medical, Dental, and Vision

  • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs and company match of charitable contributions

  • Family Planning Support

  • Flexible Work Paths

  • Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


Cambridge, MA

Worker Type


Worker Sub-Type


Time Type

Full time