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J&J Family of Companies Senior Scientist, Proteomics in Cambridge, Massachusetts

Senior Scientist, Proteomics - 2306141495W


Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies, the largest health care company in the world, is recruiting for a Senior Scientist, Proteomics, for our site in Cambridge, MA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at (file:///C:/Users/jamie yacco/AppData/Local/Microsoft/Windows/Temporary Internet Files/Content.Outlook/JHNHJA6O/ and follow us @JanssenGlobal.

Do you want to use your hard earned skills and drive to make a difference in the lives of patients? This candidate will join the Discovery Proteomic Platforms (DPP) group within the Discovery Technologies and Molecular Pharmacology (DTMP) department of Therapeutics Discovery, to apply groundbreaking approaches to proteomic analysis. This effort will support the identification and development of small and large molecule therapeutics for diseases within Oncology, Immunology, Infectious Diseases, Neuroscience, and Cardiovascular and Metabolic Diseases. Work in an exciting, interdisciplinary environment, overlapping the different stages of the discovery pipeline. Lead a team dedicated to deploying groundbreaking mass spectrometry proteomics technologies to optimize biologic therapeutics and identify translatable biomarkers from the lab to the clinic. With your help, we will drive development of medicines for our patients!

Key Responsibilities:

  • Plan, oversee and perform wet lab proteomic activities for biomarker discovery and enrichment of HLA presented peptides for therapeutic optimization.

  • Apply high efficiency proteomics sample preparation methodologies across many experiment types (global proteomic profiling, immunoprecipitation, affinity, PTM analysis).

  • Collaborate with bioinformatic and wet lab colleagues from within the proteomics group to drive experiments across the drug discovery portfolio.

  • Demonstrate creativity and apply novel approaches to solving scientific problems. Propose novel and practical ideas, aligned with scientific strategies and demands.



  • A Doctorate is required (in Analytical Chemistry, Biochemistry, Molecular Biology, Pharmacology, Immunology, or a related field) is required

Experience and Skills:


  • A minimum 5 years experience of proven experience in a proteomics laboratory setting is required, preferably including 2 or more years in a drug discovery biotech or pharmaceutical environment is required

  • Experience with liquid chromatography (Waters nanoAcquity or Thermo EASY-nLC or UltiMate 3000) and mass spectrometry (Thermo QE, Exploris, Eclipse, Lumos or Bruker timsTOF) instrumentation is required

  • Experience processing and analyzing large scale global proteomic datasets is required

  • Strong organizational skills and the ability to handle several projects at a time is required

  • Excellent interpersonal skills with the ability to interact successfully with diverse colleagues is required


  • Proficiency with lab liquid handling automation (Beckman Biomek, Hamilton Microlab STAR, TECAN Fluent, Dynamic Devices Lynx) use is preferred

  • Experience planning and performing immunopeptidomic (MHC class I or 2) experiments is preferred

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit

Primary Location NA-US-Massachusetts-Cambridge

Organization Janssen Research & Development, LLC (6084)

Job Function R&D

Req ID: 2306141495W