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Editas Medicine Research Associate, Molecular Bioanalytics in Cambridge, Massachusetts

At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.

We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.

Together, we are leading the way towards a healthier and more equitable future.

Position Summary

Editas Medicine is seeking a highly motivated and creative bioanalytical Research Associate to join our DMPK, Nonclinical Safety and Translational Sciences (DSTS) team. In this role, you would report to the Sr. Scientist of Molecular Bioanalytics and be responsible for supporting ADME, biodistribution, PK/PD and bioanalytical activities. This individual will be responsible for executing stage-appropriate molecular bioanalytical assays in support of DMPK, tox, biodistribution and PK/PD studies. The ideal candidate will have strong technical skills in PCR-based methods (ddPCR and/or TaqMan PCR), a broad understanding of drug discovery and development, and ability to work collaboratively with key partners in a matrix team structure.

Key Responsibilities:

As the Research Associate, you will be responsible for:

  • With minimal supervision, executing on routine workflows for bioanalytical method development and sample analysis using techniques such as molecular bioanalytical assays (qPCR, ddPCR) in support of non-clinical quantitative bioanalysis.

  • Independently execute and contribute to the development of PCR-based methods, sample analysis, data generation and report writing.

  • Develop nucleic acid extraction (DNA/RNA) and quantification from a broad-spectrum animal tissues.

  • Execute bioanalytical assay development strategies to characterize ADME, PK and biodistribution properties of the drug product and address key scientific questions.

  • Ensure that the data obtained is of the highest quality, timely generated

  • Write bioanalytical assay protocols, ROPs/SOPs.

  • Model behaviors of a strong technical contributor and team player.

  • Work cross-functionally within the organization.

  • Ensure compliance with electronic notebooks (ELN), high data integrity and company policies.

Requirements

The ideal candidate will possess:

  • Bachelor’s/Master’s degrees with 0-3 years[AG1] relevant industry.

  • Experience in conducting quantitative bioanalysis using molecular bioanalytical techniques such as qPCR, ddPCR to support discovery and development projects.

  • Independently design, execute and analyze experimental results and effectively communicate them.

  • Demonstrated knowledge and experience in establishing molecular bioanalytical methods, for a variety of therapeutic modalities, ideally in preclinical development.

  • Excellent communication skills and proven ability to collaborate with interdisciplinary teams, along with exceptional scientific thinking and problem-solving skills.

  • Experience with gene editing or gene delivery technologies and lipid nanoparticle delivery is highly desired.

    [AG1]0-3 years?

Benefits

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Join us at the forefront of genetic innovation and be a key contributor to Editas Medicine's mission of redefining healthcare through cutting-edge genetic technologies.

Fostering Belonging. Fueling Innovation. Transforming Lives.

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