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Sage Therapeutics Associate Director, Medicinal Chemistry in Cambridge, Massachusetts

SAGE Therapeutics is searching for a creative, resourceful, integrative thinker for an important role that is responsible to lead our Medicinal Chemistry programs focusing on small molecule drugs for CNS disorders. A demonstrated ability to thrive in a dynamic, fast-paced, start-up matrix environment will be essential as well as strong managerial and organization skills in an outsourced setting. A strong track record in drug discovery and chemistry team leadership is essential. The role requires an individual with a proven track record of delivering quality development candidates and an exceptional grasp of the entire interdisciplinary drug discovery process from lead generation to development candidate nomination. Additionally, the candidate will have demonstrated highly tuned people management, organizational and decision-making skills.

Roles and Responsibilities (Essential Functions)

  • Design, implement and execute medicinal chemistry strategies at various CRO’s.

  • Establish partnering strategies and effectively plan resource allocation to achieve team goals

  • Provide scientific and managerial leadership in an outsourced Medicinal Chemistry environment

  • The ability to work and influence drug discovery cross-functional teams is essential

  • Provide timely and well-organized reports to project teams and senior management team forums

  • Collaborate effectively with other departmental managers and functions.

Experience, Education and Specialized Knowledge and Skills

Must thrive working in a fast-paced, innovative environment while remaining flexible, proactive, resourceful and efficient. Excellent interpersonal skills, ability to develop important relationships with key stakeholders, ability to identify issues and raise to key stakeholders in order to develop relevant and realistic plans, programs and recommendations

Basic Qualifications

  • Doctoral degree (PhD) or equivalent in synthetic organic chemistry or medicinal chemistry

  • 10+ years of experience in the pharmaceutical industry, with a strong track record of scientific innovation, and delivery of clinical candidates

  • In-depth knowledge of the entire drug R&D processes, expertise in ADME/PK, pharmacology, CMC, formulations and computational chemistry

Preferred Qualifications

  • A natural leader with effective organizational, interpersonal, communication and managerial skills who is able to motivate and inspire others

  • Demonstrated technical proficiency, scientific creativity, independent thought, and ability to effectively collaborate with others

  • Excellent written and oral communication skills are required

  • Ability to foster positive working relationships across the organization; in particular with functional leads, program leads and senior leadership

  • Experience working with all levels of management and consulting with key business stakeholders. An ability to influence for greater outcomes.

  • Strong team player that has a patient-centric approach and is solution oriented.

  • Attention to detail and the ability to work individually, within a multi-disciplinary team, as well as with external partners and vendors.

  • Embrace our core values: Put People First, Do Big, Be Accountable, Grow through Learning and Change, and Work Fun.

  • Excitement about the vision and mission of Sage.

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All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

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We value our relationships with professional recruitment firms. To protect the interests of all parties, and given the large volume of inquiries received from third-party placement agencies, we are not able to respond to all agency inquiries. We do not accept unsolicited resumes from any source other than directly from candidates for current or future positions. Submission of unsolicited resumes in advance of a signed agreement between our company and a placement agency does not create an implied obligation and, if an unsolicited candidate represented by a placement agency is hired, we are not obligated to pay a fee. Only approved recruitment firms will be allowed to provide services to Sage Therapeutics, Inc.

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