Job Information
Children's Hospital Boston Research Assistant I-Kohlgruber Laboratory in Boston, Massachusetts
74785BRJob Posting Title:Research Assistant I-Kohlgruber LaboratoryDepartment:Medicine-Allergy and Immunology AutoReqId:74785BRStatus:Full-TimeStandard Hours per Week:40 Job Posting Category:ResearchJob Posting Description:The Kohlgruber Lab investigates the immune-specific basis of human diseases and applies high-throughput molecular, genetic, and immunological assays to decipher immune system specificities and interactions. We combine human and mouse immunology, with single-cell transcriptomics, synthetic biology, and immune-receptor specificity screening approaches to understand the molecular underpinnings of autoimmunity, cancer, and infectious disease. Our work lies at the intersection of translational immunology and biotechnology, where we seek to pioneer innovative strategies to improve our ability to interrogate and modulate the immune system and leverage our findings toward the development of precision vaccines and immunotherapeutics.
We seek a responsible, conscientious, and detail-oriented individual to join our team as a Research Assistant I at Boston Children’s Hospital. The individual will work closely with senior lab members on an exciting research project dissecting the role and specificity of T cells in rheumatoid arthritis and cancer. The research will require that the individual be a keen learner, have excellent communication skills, be comfortable with new technology, and work as a member of a highly collaborative team. The research assistant will also be a key contributor to the research and co-authorship on publications is supported.
This Research Assistant I will be responsible for:
Culturing mammalian cells using sterile techniques.
Cellular analysis including flow cytometry, DNA / RNA isolation, PCR, western blot, and other molecular biology techniques.
Learning and performing genomics technologies including T cell antigen discovery screens and next-generation sequencing library preparation.
Maintaining accurate, detailed, and up-to-date records regarding all procedures performed and results obtained; identifying and documenting variations that may affect the validity of the experiment.
Data collection and analysis. Performing quality control, monitoring data for accuracy, and discussing results within agreed-upon timelines with supervisor and/or mentor.
Ordering and stocking laboratory supplies and general laboratory maintenance.
Providing technical research support to other laboratory members including graduate students, postdoctoral fellows, and other professional staff.
Attending and engaging in weekly lab meetings and participating in internal meetings to share results and plan experiments.
Operating instruments such as flow cytometers, cell sorters, and microscopes.
Complying with safe laboratory practices following institutional research guidelines.
In order to qualify you must have:
Bachelor’s degree in biology or other STEM-related disciplines; MA or MS in these areas will also be considered.
Wet laboratory research experience (immunology preferred but not required).
Proficiency with molecular biology laboratory techniques and willingness to work with human samples.
Strong organizational, management, and communication skills, and an ability to recognize and prioritize responsibilities.
Advanced computer skills, including the ability to develop technical documents and presentations.
High level of initiative and motivation; ability to work independently and with a team.
Willingness to make a two-year commitment to the position.
Boston Children’s Hospital offers competitive compensation and unmatched benefits including flexible schedules, affordable health, vision and dental insurance, childcare and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.Office/Site Location:BostonRegular, Temporary, Per Diem:Regular Remote Eligibility :Onsite Only