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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Eli Lilly and Company is seeking a Therapeutic Editing Lead to join our team in Boston, MA.

Come join the rapidly expanding Gene Editing team at Eli Lilly! We are responsible for inventing, characterizing, and advancing novel genome editing reagents for a myriad of clinical applications. Our team works cross-functionally within our organization across multiple disease areas and platforms. Our goal is to deliver on the promise of gene editing to patients around the world.

Job Responsibilities:

• Lead efforts cross-functionally with Lilly’s best-in-class expertise in Diabetes, CNS, Immunology, and other areas to develop novel editing programs

• Act as the portfolio lead for pre-clinical editing programs. This will include mentoring individual program leaders. Leadership through Phase1/Phase2 trials may also be needed.

• Build and develop the team to support the development of gene editing assets

• Direct efforts within the Off-Target team to quantify risk profiles in therapeutically relevant cell models

• Participate, lead, or evaluate external research programs to bolster the genetic medicine portfolio at Lilly.

• Support the broader program in design and execution of key in vivo studies both internally and through CROs

Basic Qualifications:

• PhD in scientific field with 5+ years related work experience.

Additional Skills/Preferences:

• Mastery of CRISPR-based editing in translational models. This includes primary cells, pre-clinical disease models, and large animal IND-enabling models.

• Direct experience leading regulatory submissions for gene editing products.

• Deep scientific knowledge of lipid nanoparticles and AAV packaging of gene editing components

• Significant experience in either liver biology or neurodegeneration.

• Strong background into molecular biology assays, including qPCR, dPCR, HPLC, MS, and related technologies needed for advanced characterization of editing.

Additional Information:

• This role may require up to 10-15% travel for conferences or training and will include the opportunity to mentor and train junior scientists. The position is located at 15 Necco St, Boston, MA 02210. Full time (40 hours/week). To apply, submit resume via this site.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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