Massachusetts Jobs

74727BRJob Posting Title:Biostatistician IDepartment:Medicine-NephrologyAutoReqId:74727BRStatus:Full-TimeStandard Hours per Week:40 Job Posting Category:ResearchJob Posting Description:The focus of the Sampson Lab at Boston Children’s Hospital/Harvard Medical School is to discover the molecular basis of nephrotic syndrome through human genomics to inform mechanisms, treatments, and cures for this disease (http://sampsonlab.org). We integrate genomics data with other molecular and clinical datasets to discover the biological and clinical impact of the disease-associated genomic variants we discover. We also focus on using large Biobanks to empower genomic discovery for NS. Finally, we are also using new technologies and developing analytic strategies to make definitive genomic diagnoses for patients.

We now seek an excellent biostatistician with experience analyzing genomics data in the context of molecular association studies (i.e. GWAS, eQTL, pQTL) and studies relating molecular signatures to clinical phenotypes studies. We are most interested in applicants with excellent skills in biostatistics, as well as experience with statistical genetics analyses. Experience with genomic discovery studies using population- or electronic health record–based biobanks is a plus.

The Sampson Lab is located at Boston Children’s Hospital and is affiliated with Harvard Medical School, the Broad Institute of MIT and Harvard, and Brigham & Women’s Hospital. It is well-funded through multiple Federal grants and other resources. It is a vibrant, highly collaborative, and multidisciplinary environment made up of nephrologists, computational geneticists, biostatisticians, and epidemiologists, and bench researchers.

This Biostatistician will be responsible for:

• Designing, troubleshooting, and analysis of diverse genomic discovery efforts using our own genomic & phenotypic data & those aggregated from publicly available resources.

• Independent thinking and decision making related to study design and analysis.

• Demonstrate attention to detail and problem-solving skills.

• Excellent communication with external collaborators

• Preparation of manuscripts, grants, and presentations.

In order to qualify, you must have:

• Master's Degree in Statistics or Biostatistics

• Experience in any of the following: GWAS, rare variant association studies, genetic epidemiology studies.

• Previous work with biobanks (i.e. UKBB, AllofUs, etc) preferred

• Experience working with bioinformatics analysis pipelines, code version control (e.g., git) tools and/or experience with standard bioinformatic tools (e.g., bcftools, htslib, samtools, PLINK, bedtools) preferred

• Familiarity with reproducible data science using Jupyter Notebook or RMarkdown, or other preferred

• Statistical analysis experience and/or a working understanding of biological systems preferred

• Strong communication skills (writing and presenting)

• Programming experience in UNIX, R, and/or Python

• Familiarity with high-performance and/or cloud computing

• Evidence of prior publication(s) and conference/oral presentations

• Excellence in collaborating and interacting with others

Boston Children’s Hospital offers competitive compensation and unmatched benefits including flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.

Office/Site Location:BostonRegular, Temporary, Per Diem:Regular Remote Eligibility :Part Remote/Hybrid